The Santa Beach Hotel is one of the hotels in Thessaloniki that is a part of the seaside country area. The hotel is 19 km from the main town area near Agia Triada and the Neoi Epivates. The Santa Beach Hotel is 10 minutes' drive from the international airport, and about 20 minutes from the rail station in downtown Thessaloniki.

There are 80 rooms at the Santa Beach Hotel, available as standard rooms and suites. Rooms have private balconies, individualized air conditioning control, satellite television service, safe boxes, mini bars, direct dial telephones, and en suite bathrooms. Non-smoking and handicapped accessible rooms are available by request.

The Santa Beach Hotel is a four level building with a large garden area and one of the few ISO 9001 certifications in Greece. The gardens house the outdoor swimming pool, which is open year round. There is a house restaurant offering locally inspired dishes, and the bar serves coffees and cocktails. Conference space is offered for up to 350 people. Parking is available to guests with cars.